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Drug Therapy: Yesterday, Today and Tomorrow – Basic fundamentals for the non-scientist

Alphonse J. Ingenito, Ph.D.

Pages: 216
ISBN: 978-145752-528-5
List Price: 24.95
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Available: February 2014
Edition: Perfectbound

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Virtually all of us, at one time or another in our lives, have relied on drug therapy for treatment of illnesses ranging from minor to life threatening. Many wonder just what these agents are doing to us, , good, bad or indifferent. Perhaps we feel that we do not have the knowledge to be able to evaluate the impact of drugs on us. This book provides a practical approach to understanding the reasons, rationale and scientific basis for successful drug therapy. The approach is a general one, with concepts applying to many drug classes. The target readership is the average layperson having only a limited science background. Pre-professional health science students, practical nurses, home health aides, government employees, drug salesmen, lawyers, legislators and anyone whose employment requires a general understanding of drug therapy would find this text both informative and useful. The book follows a logical progression, beginning with the ancient origins of drugs and herbal materials and progresses to contemporary pharmacotherapy. The early chapters explore how drugs are discovered, tested, evaluated in humans and then marketed. This is followed by a general consideration of how drugs affect bodily functions and in turn how the body’s functions modify drug effects. The nature and reasons for adverse effects of drugs (e.g. side effects, drug allergies, drug toxicity and drug interactions) are presented. A common sense approach is used to aid in understanding the ins and outs of over-the-counter drugs, vitamins, herbal medicines and nutriceuticals. A final chapter offers predictions on what changes and advancements we might expect in the decades ahead.

Dr. Ingenito was born on Oct. 8, 1932 in Harrison, NJ, USA, where he attended public schools. He earned the B.S. in Pharmacy at St. John’s University, New York; the M.S. in Pharmaceutical Sciences at Rutgers University, Newark, NJ and the Ph.D. in Pharmacology at the New Jersey College of Medicine at Newark. He was a licensed pharmacist for many years in New York, New Jersey and North Carolina and practiced retail pharmacy for a time in each state. He served in the US Army for 2 years as a pharmacist in Korea. His teaching began as a graduate student assistant instructor at Rutgers University and continued at the University of Wisconsin and the New Jersey College of Medicine. His faculty positions included teaching and research for 10 years at the Albany (NY) Medical College and for 25 years at the East Carolina University School of Medicine, Greenville, NC where he retired in 2001 as Emeritus Professor of Pharmacology. He currently continues to teach there on a volunteer basis. His teaching career to medical, pharmacy, nursing, physician assistant, master’s and Ph.D.- level graduate students and other allied health students has spanned over 50 years. He was a research mentor to numerous graduate students in pharmacology. His own research was concerned with the neural actions of antihypertensive drugs, neurotransmitter actions in brain, the pharmacological actions of tobacco smoke constituents and the neural actions of opioid peptides. He has authored or co-authored over 60 scientific papers on his research and has published a variety of educational materials in his field. During his active career he maintained membership in 8 different professional societies; serving for many years as a member of the Board of Regents of the American College of Clinical Pharmacology. He is married and has 4 children and 7 grandchildren. His hobbies include choral and barbershop quartet singing and gardening.